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Top Countries with the Highest HIV Rates in 2025
Eswatini Leads with the Highest HIV Prevalence
Eswatini continues to hold the position as the country with the highest HIV infection rate. About 28.3% of its population aged 15-49 are living with HIV, reflecting ongoing challenges in infection control and healthcare initiatives. This persistent high rate underscores the urgent need for targeted prevention and treatment programs in the region.
Lesotho and Botswana Follow
Close behind Eswatini, Lesotho reports an HIV rate of 23.4%, and Botswana’s prevalence stands at 22.35%. Both nations face significant public health challenges, with their high HIV burdens impacting socioeconomic development, workforce health, and healthcare systems.
Zimbabwe’s HIV Situation
Zimbabwe’s HIV prevalence remains critically high at 21.6%. Despite extensive intervention efforts over the years, the country continues to grapple with controlling the virus, emphasizing the importance of sustained, comprehensive healthcare strategies.
South Africa and Namibia’s HIV Footprint
South Africa has a notable HIV infection rate of 14%, reflecting the country’s ongoing fight against the epidemic. Namibia’s rate, at 13%, also highlights the broad regional impact of HIV/AIDS in southern Africa. Both nations are actively investing in prevention, testing, and treatment but face evolving challenges such as stigma and resource allocation.
Zambia’s Mixed Progress
With an HIV prevalence of 12.5%, Zambia has made noticeable progress compared to neighboring countries. Still, the rate indicates that HIV remains a significant public health issue requiring continued focus on education and access to care.
Countries with Moderate HIV Rates
Kenya has an estimated 5.1% of its population infected, marking a reduction compared to previous years but still representing a substantial health concern. Cameroon follows with a rate of 4%. Both countries are actively working toward reducing these numbers through national campaigns, awareness programs, and improved healthcare access.

Note: Image provided for visual context of the global HIV prevalence.
Countries with Notable Progress and Low HIV Rates
Haiti, Nigeria, and Liberia show lower infection rates at 2.2%, 2.1%, and 1.5%, respectively. These countries have seen success through targeted health initiatives and increased awareness campaigns.
Further down the scale, several nations, including Thailand, Ukraine, Ethiopia, and Brazil, report rates below 1.2%. This trend reflects advancing public health efforts and increased access to antiretroviral therapy, which significantly reduces transmission rates.
Nearly HIV-Free Countries
Countries like Japan, Switzerland, Italy, and Australia have been able to maintain extremely low HIV prevalence rates, generally below 0.2%. Japan’s rate is the lowest at just 0.02%, illustrating the effectiveness of comprehensive healthcare systems, preventative measures, and education.
Global Overview
Worldwide, the HIV prevalence among people aged 15-49 sits at approximately 0.7%. While some countries have effectively contained the virus within their borders, others continue to experience high rates that demand intensified efforts.
Summary: A Global Perspective on HIV in 2025
Despite remarkable progress in many nations, the battle against HIV/AIDS remains ongoing. Sub-Saharan Africa continues to bear the brunt of the epidemic, with Eswatini, Lesotho, Botswana, and Zimbabwe experiencing the highest infection rates. Conversely, countries like Japan, Switzerland, and Australia exemplify successful strategies in reducing transmission.
The data underscores the importance of sustained investment in healthcare infrastructure, education, prevention, and treatment programs. Maintaining global momentum and addressing disparities between countries is essential to controlling and ultimately ending the HIV/AIDS epidemic.
Data Source: UNAIDS, 2024 Estimates



