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Home » How to Play Vex in Borderlands 4: Completing and Solving Tips

How to Play Vex in Borderlands 4: Completing and Solving Tips

Emily Smith by Emily Smith
September 18, 2025
in Gaming
Reading Time: 4 mins read
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How to Play Vex in Borderlands 4: Completing and Solving Tips
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As you explore Borderlands 4, you’ll choose one of four unique characters, each with special skills and different combat styles. Every character has its own flavor, appealing to various preferences and experience levels. Among them, Vex the Siren stands out as one of the best choices, and here’s why.

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Vex’s skill trees and fighting style make clearing Rippers and Manglers much easier. Her abilities allow her to move around the map freely, summon spectral allies, and buff herself while attacking enemies. Whether you prefer to attack solo or with friends, each skill tree offers a different approach, so you can pick the one that suits you best.

### Siren Class Overview

The Siren class plays more like a caster, even though it doesn’t have traditional spells. Instead, Vex summons spectral allies who fight for her, boost her abilities, and attack enemies. Her role is versatile, allowing you to surround enemies, team up with others, or take on foes alone.

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### Vex Skill Trees

| Tree Name | Description | Best Use |
|———————–|————————————————————————————————–|——————————|
| The Fourth Seal | Summons spectral clones called Reapers or Specters to distract enemies with gun damage and taunt. Good for surrounding enemies and dividing their attention. | Solo |
| Here Comes Trouble | Summons a tiger-like ally called Trouble that changes form based on Vex’s attunement and can become a stronger version. Helps handle groups and supports damage. | Campaign |
| Vexcalation | Lets Vex cast Eldritch Blast and increases movement speed. Deals damage on impact, with reduced cooldown if gun damage is dealt. | Multiplayer |

### Best Campaign Build for Vex

For leveling up during the campaign, focus on fast-paced weapons like SMGs and assault rifles, especially ones that let you switch between affinities quickly. The Here Comes Trouble tree is ideal, summoning Trouble to help deal with groups while you stay safe. The perks in this tree emphasize balancing damage and utility, letting Trouble act as a distracting, damage-dealing ally that keeps enemies at bay.

In early gameplay, prioritize buffing Trouble with skill points, and take advantage of kill bonuses to keep your momentum. Use Blink Strike to draw enemy fire, and once at level 17, pick the Hexus Nexus augment to make enemies prefer attacking Trouble, taunting them away from you. The Unsealed ability is crucial—upon defeating enemies, it boosts health regeneration and damage, making Trouble more durable and effective.

### Key Skills for Campaign

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– Grave Sustenance: Extends your action skill duration.
– Grave Command: Refreshes Trouble’s command and respawn cooldowns.
– Yowl and Bay: Increases gun damage when commanding Trouble.
– Vorpal Fiends: Boosts critical hit damage for Trouble.
– Shocking Attunement: Enhances movement and gun damage when attuned to shock, with effects carrying over briefly.
– Infusion: Adds damage boost when using Repkits, scaled to your current attunement.
– Guns and Needles: Lowers cooldown on using Repkits.
– Grave Sights: Raises critical hit damage and gun handling.
– Fiendish Invigoration: Boosts movement speed and fire rate when using Repkits.
– Target Prescience: Increases critical hit chance against enemies.
– Channeling: Extends action skill and attunement durations.

### Solo Build for Vex

To take on enemies alone, invest in the The Fourth Seal tree, summoning multiple Phase Clones that distract foes with gun and melee attacks. These clones mimic Vex’s appearance and attunements, allowing you to adapt to various elemental damages and strategies. Swapping between attunements lets you exploit elemental reactions for increased damage over time.

This approach excels for farming bosses alone. Prioritize Maliwan weapons, which are excellent for their affinity attunements, but don’t hesitate to choose any weapon type you prefer—assault rifles, shotguns, or snipers. Summon clones to keep enemies occupied while you attack from strategic positions. Remember, clones are temporary, so keep track of their lifespan and plan your attacks accordingly.

To maximize your effectiveness, equip the Coven augment for health regeneration and increased critical chance for your clones. Using Wither to trigger status effects and the Dark Pact ability will keep your clones alive longer and boost your damage and healing, especially useful when you need to sustain through tough fights.

### Multiplayer Build for Vex

For team play, focus on max damage output, utilizing the Incarnate skill tree and Vexcalation. This build transforms Vex into a drain-based character, sapping health from enemies and using Eldritch Blast alongside her guns to reduce cooldowns. Embrace this vampire-like style, draining health, and healing yourself as you deal damage.

Prioritize the Geistwave skill to cause explosive damage to multiple foes, with increased damage after detonation. Pair it with the Witchy Trigger Finger augment to replenish ammo via Phase Explosions, letting you stay mobile and aggressive during fights. Keep emergency ammo on hand, as this build depends on switching weapons often for maximum damage.

Finish with the Heartpiercer ability, sacrificing some health to unleash a piercing wave from Eldritch Blast that damages enemies and heals allies. This boosts your raw damage and utility, making you a true support and damage dealer simultaneously.

When selecting weapons, stick to Jakobs guns for their high Kinetic damage. Avoid elements that don’t complement this build, as pure Kinetic damage maximizes Vex’s potential. Items like Vampiric Throwing Knives add lifesteal, while shields like Firewerks or Evasive Retort increase mobility and damage output.

### Best Skills for Damage and Survival

– Leeching Attunement: Lifesteal and faster reload when attuned to Kinetic.
– Bloodletter: Critical hits apply bleed damage over time.
– Material Components: Increases Kinetic damage and effect damage.
– Conjuration: Damage scales with shield health; provides damage reduction when health is low.
– Grave Vitality: Increases max health and health regen.
– Blood Shot: Converts damage into Kinetic damage after using a Repkit.
– Essence Leech: Lifesteal that doubles with Incarnate.
– Blood is Power: Bonus Kinetic damage and healing based on health sacrificed.

Building Vex is flexible. Mix abilities and skill points to suit your preferred style, whether it’s a magic-wielding caster, an agile solo hunter, or a team-oriented damage dealer. For beginners, the Here Comes Trouble tree offers straightforward play, while the advanced options like Vexcalation provide greater control and challenge for experienced players.

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Tags: Borderlands 4GameplayGamingguideHow To Play VextipsTriple-A GamesTutorialVexVideo Game
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Emily Smith

Emily Smith

Emily is a digital marketer in Austin, Texas. She enjoys gaming, playing guitar, and dreams of traveling to Japan with her golden retriever, Max.

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