Best Build and Relics for the Regent in Slay the Spire 2: Completing and Solving Strategies

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Slay the Spire 2 can be quite challenging, especially if you’re new to deck-building games. With numerous cards, five distinct characters, many Relics, and tough enemies, managing everything to secure a win is a lot to handle. Among the playable heroes, The Regent is one of the more complex options.

The Regent has some of the strongest and weakest cards in the game. When built properly, this character can become incredibly powerful. If you want to improve your chances of winning with this cosmic ruler, here are some of the best cards and relics to keep an eye out for.

The Best Regent Build

Before diving into the specifics, keep in mind that this isn’t the only effective way to play The Regent. Build can be very strong, so don’t feel pressured to follow this exact strategy every time to succeed.

The Archetype

The core strategy with The Regent most often involves the Star mechanic. Think of Stars as a secondary resource you need to gather and spend. The deck focuses on stacking up Stars and then using them for utility or heavy damage spells. Building this kind of deck can be tricky because it depends on balancing Star-generating cards with those that make use of Stars. I recommend searching actively for Star-related cards early in Act 1.

Your main plan is to gain an advantage by accumulating and spending Stars through various Power cards, then hitting enemies with big, multi-hit attack spells. Proper sequencing is vital, as you’ll want to maximize the Stars spent and used each turn. During early turns, especially against bosses, your goal is to set up for a massive hit on one enemy. As you progress through Acts, thinning your deck of basic Strike and Defend cards will improve consistency, ensuring most of your draws revolve around the Star mechanic.

The Best Cards

Keeping an eye out for key cards is essential. These are divided into core, payoff, and support categories.

Core Cards – Generate or utilize Stars efficiently:

Name	Energy/Star Cost	Effect
Genesis	2 Energy	At the start of your turn, gain 2 Stars.
Glow	1 Energy	Gain 1 Star. Draw 2 cards.
Royal Gamble	0 Energy / 5 Stars	Gain 9 Stars. Exhaust.
Shining Strike	1 Energy	Deal 8 damage. Gain 2 Stars. Place on top of deck.
Hidden Cache	1 Energy	Gain 1 Star. Next turn, gain 3 Stars.
The Sealed Throne	1 Energy / 3 Stars	Play a card, gain 1 Star.
Convergence	1 Energy	Next turn, gain 1 Energy and 1 Star. Retain hand.
Knockout Blow	3 Energy	Deal 30 damage. If it kills an enemy, gain 5 Stars.

When aiming to create Stars, focus on Genesis, Glow, Royal Gamble, and Hidden Cache. Genesis stands out as the top Star generator, offering two Stars each turn for just 2 Energy. Glow is also valuable, adding a Star and drawing cards. Royal Gamble is a powerful spell to look for; it provides a big Stars boost and synergizes well with payoff spells. Shining Strike is a consistent damage option that can be recycled to maximize damage output, especially in fights with multiple enemies. Knockout Blow is a high-damage card that, if it finishes off an enemy, rewards you with multiple Stars, creating strong combo opportunities.

Damage Spells – Focus on the following to finish fights:

Name	Energy/Star Cost	Effect
Radiant	0 Energy	Deal 3 damage for each Star gained this turn.
Seven Stars	2 Energy / 7 Stars	Deal 7 damage 7 times across all enemies.
Stardust	0 Energy / X Stars	Deal 5 damage X times to random enemies.
Black Hole	1 Energy	Whenever you gain or spend a Star, deal 3 damage to all enemies.
Comet	0 Energy / 5 Stars	Deal 33 damage, apply Vulnerable and Weak.
Crescent Spear	0 Energy / 1 Star	Deal 6 damage plus additional damage based on Star cards.

For closing out fights, Radiant and Stardust are your top choices. Radiant can devastate enemies if you’ve built up a lot of Stars in one turn, especially with spells like Royal Gamble or Hidden Cache. Stardust makes good use of accumulated Stars, dealing damage multiple times.

Seven Stars costs more but acts as an excellent Area of Effect (AoE) spell to wipe out groups of foes. Black Hole offers continuous damage as you generate Stars, and Comet provides burst damage while applying vulnerability, perfect before casting high-damage spells like Radiant. Crescent Spear is situational—useful early on but replace it as your deck improves.

Support Cards and Utility

To maintain defense and utility, include cards like:

Name	Energy/Star Cost	Effect
Cloak of Stars	0 Energy / 1 Star	Gain 7 Block.
Child of the Stars	1 Energy	When you spend a Star, gain 2 Block per Star.
Big Bang	0 Energy	Draw 1 card, gain 1 Energy and 1 Star, Forge 5, Exhaust.
Reflect	1 Energy / 3 Stars	Gain 17 Block. Blocked attacks reflect damage.
Decisions, Decisions	0 Energy / 6 Stars	Draw 3 cards and play a Skill 3 times, then Exhaust.
Void Form	3 Energy	End turn. The first 2 cards you play this turn are free.

Prioritize Child of the Stars, Reflect, and Cloak of Stars for defense. Child of the Stars is especially good at quickly gaining Block based on Star expenditure, helping you set up for big turns. Big Bang and Void Form are versatile, effective cards in almost any deck: Big Bang boosts your hand and resources, while Void Form allows you to play powerful turns with reduced costs.

The Best Relics

Relics can provide passive benefits that complement your strategy. The most useful ones include:

Name	Effect
Galactic Dust	For every 10 Stars spent, gain 10 Block.
Chemical X	Enhances the effects of X-cost cards by +2.
Lunar Pastry	At the end of your turn, gain 1 Star.
Ice Cream	Energy is conserved between turns.
Dolly’s Mirror	When acquired, duplicate a card in your deck.

Galactic Dust improves your defensive capabilities by turning Star spending into additional Block. Chemical X boosts your big, expensive X-cost spells, increasing their impact. Lunar Pastry is a steady source of additional Stars each turn, useful if your draw luck isn’t perfect. Ice Cream is a passive bonus that allows you to save Energy for larger turns. Dolly’s Mirror can help shore up weaknesses by duplicating key cards, especially high-impact spells.

Focusing on these Relics allows you to maximize your Star mechanic, inflate your damage potential, and maintain protection against enemies’ attacks.