Eric Dane, ‘Grey’s Anatomy’ Star, Dies at 53 Following ALS Battle

DIGITAL PHABLET – Beloved actor Eric Dane passes away after a courageous battle with ALS.

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Eric Dane, renowned for his role as the charismatic plastic surgeon nicknamed “McSteamy” on the popular ABC medical series “Grey’s Anatomy,” has died. He was 53 years old.

Melissa Bank, his publicist, announced his passing, sharing that he had been battling ALS, a neurological disorder also known as Lou Gehrig’s disease, which progressively impairs muscle movement, speech, and eventually breathing.

In her statement, Ms. Bank expressed, “He spent his final days surrounded by close friends, his loving wife, and his two beautiful daughters, Billie and Georgia, who meant everything to him.”

Eric Dane died ten months after revealing in an April 2025 interview with People magazine that he had ALS. Over the following months, he openly discussed the struggles of living with the disease as it worsened, through interviews and social media updates. ALS, or amyotrophic lateral sclerosis, often limits individuals to living only two to five years post-diagnosis. However, ongoing clinical research offers hope for extending patients’ lives by a few months.

In 2025, Dane appeared on “Good Morning America” with Diane Sawyer, sharing, “I will never forget those three letters.” He added, “I’ll deal with it as soon as I wake up.” He talked about how his right arm had already stopped functioning and emphasized, “This is real, not a dream.”

Later that year, during a program aimed at raising awareness, Dane sat in a chair and declared, “I am an actor.” His speech was slightly slurred as he shared, “I’m a dad, and I live with ALS now.” He urged viewers to help push for treatments and increased funding to combat the disease.

Born as David William Dane in San Francisco on November 8, 1972, he was raised by William Dane, an architect and interior designer, and Leah (Cohn) Dane, a homemaker. He had a younger brother.

During high school, Dane excelled in sports and developed an interest in acting after starring in a school production of Arthur Miller’s “All My Sons.”

He moved to Los Angeles in 1993, launching his career with a role on “The Wonder Years.” This led to smaller appearances on hit series like “Saved by the Bell” and “Married… with Children.”

Early in his career, Dane secured supporting roles that highlighted his boyish charm. His debut on TV was as a doctor in ABC’s medical drama “Gideon’s Crossing.” He also played a newspaper publisher in San Francisco and was a love interest for Alyssa Milano’s character Phoebe in “Charmed,” the CW series about three witch sisters.

In film, Dane appeared in 2006’s “X-Men: The Last Stand” as a mutant capable of transforming into different versions of himself. Two years later, he co-starred in “Marley & Me,” a comedy based on real-life events about a married couple of reporters and their mischievous yellow Labrador retriever.

He married Rebecca Gayheart in 2004, and she, along with their two daughters, Billie Beatrice and Georgia, was present when he passed away.

The breakthrough role that made Dane widely recognizable was in “Grey’s Anatomy,” a medical soap opera that premiered in 2006. He played Dr. Mark Sloan, the charming, blue-eyed head of plastic surgery at a fictional hospital in Seattle. His character was notorious for stirring trouble weekly and earned the nickname “McSteamy” for his sultry demeanor and charismatic talk.

One particularly famous scene featured Dane shirtless, wrapped in a white towel, after a shower—a scene famously dubbed the “towel scene.” He later admitted he had no idea at the time how iconic that moment would become.

In 2025, Dane reflected in an interview with Ms. Sawyer, “It was just another scene to me back then.” He remembered how a crew member joked as he left the bathroom, “A good guy blowing smoke.”

He appeared in 139 episodes of “Grey’s Anatomy,” making it one of ABC’s most successful series since 2005.

Beyond “Grey’s,” Dane also starred as a stern but principled Navy captain in “The Last Ship,” a dystopian drama that ran for five seasons. He continued working steadily despite health challenges.

Most recently, in the latest season of HBO’s “Euphoria,” he played the father of Nate Jacobs, portrayed by Jacob Elordi. In November 2025, Dane drew from his own experience for a role as a firefighter on NBC’s “Brilliant Minds,” a medical thriller about a man struggling with his family’s acceptance of his ALS diagnosis.

Dane’s memoir, titled “Book of Days: A Memoir in Moments,” is scheduled for release in 2026 through Open Field, Maria Shriver’s publishing imprint at Penguin Random House.

He discussed his time as McSteamy and his perspective on fame in a 2015 interview with Conan O’Brien, joking, “It would be weird if you didn’t.”

He mused about his new role as a ship’s captain, joking about gaining weight while sitting at the wheel and barking commands, adding, “I think I’ll just let it go.” He also confessed, “I no longer care.”